Clinical and Radiological Features of Multiple Myeloma Patients at the University Teaching Hospital, Lusaka, Zambia

Authors

  • F Mwaba University of Zambia, School of Medicine, Department of Pathology and Microbiology, Lusaka, Zambia
  • T Kaile University of Zambia, School of Medicine, Department of Pathology and Microbiology, Lusaka, Zambia
  • K Sumbukeni University Teaching Hospital, Department of Food and Drugs, Lusaka, Zambia
  • C Chifumbe University of Zambia, School of Medicine, Department of Pathology and Microbiology, Lusaka, Zambia
  • P Nkhoma University of Zambia, School of Medicine, Department of Biomedical sciences, Lusaka, Zambia
  • H Mantina University Teaching Hospital, Department of Pathology and Microbiology, Lusaka, Zambia

DOI:

https://doi.org/10.55320/mjz.43.1.304

Keywords:

Multiple myelom, Clinical and Radiological features.

Abstract

Background: Multiple myeloma (MM) is the second most common blood cancer after lymphomas, thereby accounting for 10% of all haematological malignancies.
Objectives: To evaluate the clinical and radiological features of Multiple Myeloma at presentation in patients presenting at the University Teaching Hospital (UTH), Lusaka, Zambia.
Design: Descriptive study
Methods and Results: Record files of patients diagnosed with MM from 2008-2015 April were reviewed. Data was analysed using SPSS Version 22. The median age at diagnosis was 53.0 (range 32-81 years). From 46 patients, 25 (54%) were men and 21(46%) were females. The most frequent and common clinical and radiological  features in order of occurrence were osteolytic lesions (65%), back pain (59%), bone pain (46%), anaemia (30%), pathological fractures (26%), chest pain (26%) and fatigue (15%). Females had a higher proportion of fatigue than men with (P= 0.036). It was also observed that pathological fractures in individuals with  osteolytic lesions were statistically significant with (P=0.001).
Conclusion: It was observed that osteolytic lesions which are a radiological feature of MM were the most frequent feature of patients presenting with MM at UTH, Lusaka Zambia.

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Published

30-03-2016

How to Cite

Mwaba, F., Kaile, T., Sumbukeni, K., Chifumbe, C., Nkhoma, P., & Mantina, H. (2016). Clinical and Radiological Features of Multiple Myeloma Patients at the University Teaching Hospital, Lusaka, Zambia. Medical Journal of Zambia, 43(1), 7–11. https://doi.org/10.55320/mjz.43.1.304

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Section

Original Article