Primary Malignant Bone Tumours at the University Teaching Hospital in Lusaka Zambia


Introduction:  Primary malignant bone tumours include malignancies arising primarily from bone tissue. This is opposed to secondary bone tumours in which case the neoplastic elements arise primarily from other sites within the body and secondarily spread to bone. Primary malignant bone tumours are generally considered rare. Wherever primary malignant bone tumours occur they tend to pose serious challenges in terms of diagnosis, management and morbidity and mortality.

Clinical and Radiological Features of Multiple Myeloma Patients at the University Teaching Hospital, Lusaka, Zambia


Background: Multiple myeloma(MM) is the second most common blood cancer after lymphomas, thereby accounting for 10% of all haematological malignancies.

Objectives: To evaluate the clinical and radiological features of Multiple Myeloma at presentation in patients presenting at the University Teaching Hospital(UTH), Lusaka, Zambia.
Design: Descriptive study

Prevalence of Basal-like Breast Cancer among Indigenous Black Zambians at the University Teaching Hospital, Lusaka, Zambia

Background: Breast cancer comprises a group of very diverse diseases, which can be demonstrated at the molecular, histopathological and clinical levels. Gene expression studies using RNA microarray studies have categorised breast carcinomas into several classes. Of these basal-like tumour class has showed poor prognosis and  their  insensitivity  to  hormonal  therapy  makes therapeutic management difficult. Immunohistochemistry using certain Cytokeratins such as CK 5/6 has made it easier to identify these tumours allowing for better management.

Prevalence of subclinical Cardiovascular Disease in healthy HIV infected patients at the University Teaching Hospital in Lusaka, Zambia


Background: Cardiovascular diseases are among the leading cause of morbidity and mortality worldwide. The association between HIV and CVD has been established in many studies. However, information is still lacking on subclinical disease as well as its associated risk factors in this population. This study aimed at establishing the prevalence of subclinical CVD among clinically healthy HIV people attending their regular out- patient visits.