Background: Psychiatric co-morbidities occur more frequently in patients with epilepsy but are usually undertreated. Treatment of these disorders is key to reducing mortality via suicide and other causes. This study determined the levels of treatment of psychiatric co-morbidities at clinics in Lusaka, Zambia.

Indigenous Knowledge Systems for the treatment of Hypertension in Lusaka, Zambia: Perceptions, Knowledge and Practice


Background: A significant number of patients suffering from hypertension, a major risk factor for cardiovascular morbidity, are said to access traditional medicine (TM) for their disease management. Traditional medicine, originating from indigenous knowledge that has been passed on from generation to generation, has remained largely under-researched. There is paucity of information on the efficacy and toxicity of these remedies.

Non-Invasive Ventilation in HIV Positive patients with Sepsis and Respiratory Failure at the UTH, Lusaka, Zambia


Background: Sepsis due to respiratory disease is one of the main complications of HIV/AIDS. Audit data from the Department of Internal Medicine at the University Teaching Hospital in Lusaka, Zambia indicate that pneumonia and tuberculosis in HIV represent two of the four leading causes of death. The mortality rate has remained high despite the advances made in antimicrobial spectrum.

Transformation Agenda of World Health Organization Regional Office for Africa to the Zambian context

The focus of this special issue of the Medical Journal of Zambia is to showcase the progress made by the World Health Organization (WHO) Country Office for Zambia in domesticating the Transformation Agenda (TA) of the WHO Regional Office for Africa. This TA is the regional vision to fast track implementation of the global WHO reform. The introduction of this Transformation Agenda is timely and smoothly dovetails with the on going implementation of the national Zambia development transformation is a robust process that facilitates effective implementation of the Regional Agenda within WHO.

Prescribing Patterns and Medicine Use at the University Teaching Hospital, Lusaka, Zambia


Background: There is paucity of data on rational drug use studies at tertiary hospitals in Zambia. The aim of this study was to assess the extent of rational drug use at the adults and paediatrics outpatient departments of the University Teaching Hospital (UTH) using World Health Organization (WHO) standardized drug-use indicators.

Progress of WHO Zambia towards the WHO Reforms through Transformation Agenda


Background: WHO is going through reforms which started in 2011. The Reform process intensified when the WHO was put to the test during the Ebola outbreak in West Africa in 2014. Weaknesses observed raised widely expressed concern about the response of the WHO in emergencies. Dwindling financial resources and multiple partners interested in its mandate also largely contributed to WHO reforms. WHO African Region introduced the Transformation Agenda programme in 2015 designed to accelerate implementation of WHO reforms within Africa.