Echoviruses diagnosed in two Children presenting with Acute Flaccid Paralysis (AFP): An Illustration of the Evolving role of the Zambian AFP Surveillance Programme in the Absence of Polio


Background: The Enteric Cytopathic Human Orphan virus commonly referred to by the acronym ECHO virus has been known to cause acute flaccid paralysis (AFP). Zambia has since 1993 run a national AFP surveillance program to primarily detect and confirm poliomyelitis cases. Through this program other enteroviruses have been confirmed to be associated to the non-polio cases. We describe two patients with acute flaccid paralysis presenting like poliomyelitis and yet are non-polio cases associated with ECHO virus.

Bipolar Disorder in Child Psychiatric Practice: A Case Report


Bipolar disorder in children is unrecognized for many reasons including lack of awareness, diagnostic confusion, and the different clinical picture in children. The disorder has not been well studied in prepubertal children, despite its potentially debilitating effects on growth and development. It may be comorbid with Attention Deficit Hyperactivity disorder (ADHD) and conduct disorder (CD) or it may demonstrate features of ADHD and CD. A bipolar child should be treated using a biopsychosocial approach.

Bacteriology of Chronic Suppurative Otitis Media among Children at the Arthur Davidson Children's Hospital, Ndola, Zambia


Objectives:  The  study  aimed  to  determine  the
bacteria that cause CSOM and their sensitivity to drugs used in children attending at the Ear Nose and Throat (ENT) clinic at Arthur Davidson Children's Hospital(ADCH) in Ndola.

Primary Malignant Bone Tumours at the University Teaching Hospital in Lusaka Zambia


Introduction:  Primary malignant bone tumours include malignancies arising primarily from bone tissue. This is opposed to secondary bone tumours in which case the neoplastic elements arise primarily from other sites within the body and secondarily spread to bone. Primary malignant bone tumours are generally considered rare. Wherever primary malignant bone tumours occur they tend to pose serious challenges in terms of diagnosis, management and morbidity and mortality.

Clinical and Radiological Features of Multiple Myeloma Patients at the University Teaching Hospital, Lusaka, Zambia


Background: Multiple myeloma(MM) is the second most common blood cancer after lymphomas, thereby accounting for 10% of all haematological malignancies.

Objectives: To evaluate the clinical and radiological features of Multiple Myeloma at presentation in patients presenting at the University Teaching Hospital(UTH), Lusaka, Zambia.
Design: Descriptive study

Prevalence of Basal-like Breast Cancer among Indigenous Black Zambians at the University Teaching Hospital, Lusaka, Zambia

Background: Breast cancer comprises a group of very diverse diseases, which can be demonstrated at the molecular, histopathological and clinical levels. Gene expression studies using RNA microarray studies have categorised breast carcinomas into several classes. Of these basal-like tumour class has showed poor prognosis and  their  insensitivity  to  hormonal  therapy  makes therapeutic management difficult. Immunohistochemistry using certain Cytokeratins such as CK 5/6 has made it easier to identify these tumours allowing for better management.

Prevalence of subclinical Cardiovascular Disease in healthy HIV infected patients at the University Teaching Hospital in Lusaka, Zambia


Background: Cardiovascular diseases are among the leading cause of morbidity and mortality worldwide. The association between HIV and CVD has been established in many studies. However, information is still lacking on subclinical disease as well as its associated risk factors in this population. This study aimed at establishing the prevalence of subclinical CVD among clinically healthy HIV people attending their regular out- patient visits.